WEDNESDAY, Aug. 24, 2022 (HealthDay Information) — Sperm focus and sperm rely are improved in males with weight problems after diet-induced weight reduction, in accordance with a research revealed within the July difficulty of Human Copy.
Emil Andersen, from College of Copenhagen in Denmark, and colleagues examined acute and long-term results of weight reduction on semen parameters. The evaluation included 56 males with weight problems assigned to an preliminary eight-week low-calorie weight-reduction plan (800 kcal/day), adopted by randomization to 52 weeks of placebo and routine exercise (placebo), train coaching and placebo (train), the Glucagon Like Peptide 1 (GLP-1) analogue liraglutide and routine exercise (liraglutide), or liraglutide together with train coaching (mixture).
The researchers discovered that males misplaced on common 16.5 kg physique weight with the low-calorie weight-reduction plan, which elevated sperm focus 1.49-fold and sperm rely 1.41-fold. For males who maintained the load loss, these enhancements had been maintained for 52 weeks, however enhancements weren’t maintained in males who regained weight. No modifications had been seen in semen quantity, sperm motility, or motile sperm rely.
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“The persistent improvement of sperm concentration and count after weight loss maintained through exercise and/or a GLP-1 receptor agonist may therefore also result in improved male fertility,” the authors write.
The research was supported by a grant from the Novo Nordisk Basis, and a number of other authors disclosed monetary ties to Novo Nordisk.